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DeCS
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Descriptor English:
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Myelinolysis, Central Pontine
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Descriptor Spanish:
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Mielinólisis Pontino Central
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Descriptor Portuguese:
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Mielinólise Central da Ponte
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Synonyms English:
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Central Pontine Myelinolysis
Extrapontine Myelinolysis
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Tree Number:
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C10.228.140.163.560
C10.314.500
C18.452.132.560
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Definition English:
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A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6) |
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History Note English:
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1994
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Allowable Qualifiers English:
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Record Number:
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31291
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Unique Identifier:
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D017590
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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